|
| From | Destination | Type |
|---|
| David (DAV) | Tocumen, Panama City (PTY) | Direct | details |
| Tocumen, Panama City (PTY) | Armenia (AXM) | Direct | details |
| Tocumen, Panama City (PTY) | Aruba (AUA) | Direct | details |
| Tocumen, Panama City (PTY) | Asuncion (ASU) | Direct | details |
| Tocumen, Panama City (PTY) | Atlanta, GA (ATL) | Direct | details |
| Tocumen, Panama City (PTY) | Austin, TX (AUS) | Direct | details |
| Tocumen, Panama City (PTY) | Baltimore, MD (BWI) | Direct | details |
| Tocumen, Panama City (PTY) | Barcelona (BLA) | Direct | details |
| Tocumen, Panama City (PTY) | Barquisimeto (BRM) | Direct | details |
| Tocumen, Panama City (PTY) | Barranquilla (BAQ) | Direct | details |
| Tocumen, Panama City (PTY) | Belo Horizonte (CNF) | Direct | details |
| Tocumen, Panama City (PTY) | Benito Juarez, Mexico City (MEX) | Direct | details |
| Tocumen, Panama City (PTY) | Bogota (BOG) | Direct | details |
| Tocumen, Panama City (PTY) | Brasilia (BSB) | Direct | details |
| Tocumen, Panama City (PTY) | Bridgetown (BGI) | Direct | details |
| Tocumen, Panama City (PTY) | Bucaramanga (BGA) | Direct | details |
| Tocumen, Panama City (PTY) | Cali (CLO) | Direct | details |
| Tocumen, Panama City (PTY) | Cancun (CUN) | Direct | details |
| Tocumen, Panama City (PTY) | Caracas (CCS) | Direct | details |
| Tocumen, Panama City (PTY) | Cartagena (CTG) | Direct | details |
| Tocumen, Panama City (PTY) | Cheddi Jagan, Georgetown (GEO) | Direct | details |
| Tocumen, Panama City (PTY) | Chiclayo (CIX) | Direct | details |
| Tocumen, Panama City (PTY) | Cordoba (COR) | Direct | details |
| Tocumen, Panama City (PTY) | Cucuta (CUC) | Direct | details |
| Tocumen, Panama City (PTY) | Curacao (CUR) | Direct | details |
| Tocumen, Panama City (PTY) | David (DAV) | Direct | details |
| Tocumen, Panama City (PTY) | Denver, CO (DEN) | Direct | details |
| Tocumen, Panama City (PTY) | Dulles, Washington, DC (IAD) | Direct | details |
| Tocumen, Panama City (PTY) | Edward L. Logan, Boston, MA (BOS) | Direct | details |
| Tocumen, Panama City (PTY) | Felipe Angeles Intl., Mexico City (NLU) | Direct | details |
| Tocumen, Panama City (PTY) | Fort Lauderdale, FL (FLL) | Direct | details |
| Tocumen, Panama City (PTY) | Galeao-A.C. Jobim, Rio de Janeiro (GIG) | Direct | details |
| Tocumen, Panama City (PTY) | Guadalajara (GDL) | Direct | details |
| Tocumen, Panama City (PTY) | Guarulhos, Sao Paulo (GRU) | Direct | details |
| Tocumen, Panama City (PTY) | Guatemala City (GUA) | Direct | details |
| Tocumen, Panama City (PTY) | Guayaquil (GYE) | Direct | details |
| Tocumen, Panama City (PTY) | HARRY REID INTL AIRPORT, Las Vegas, NV (LAS) | Direct | details |
| Tocumen, Panama City (PTY) | Havana (HAV) | Direct | details |
| Tocumen, Panama City (PTY) | John F. Kennedy, New York, NY (JFK) | Direct | details |
| Tocumen, Panama City (PTY) | Jose Maria Cordova, Medellin (MDE) | Direct | details |
| Tocumen, Panama City (PTY) | Kingston (KIN) | Direct | details |
| Tocumen, Panama City (PTY) | Las Americas, Santo Domingo (SDQ) | Direct | details |
| Tocumen, Panama City (PTY) | Lester B. Pearson, Toronto (YYZ) | Direct | details |
| Tocumen, Panama City (PTY) | Lima (LIM) | Direct | details |
| Tocumen, Panama City (PTY) | Los Angeles, CA (LAX) | Direct | details |
| Tocumen, Panama City (PTY) | Luis Munoz Marin, San Juan (SJU) | Direct | details |
| Tocumen, Panama City (PTY) | Managua (MGA) | Direct | details |
| Tocumen, Panama City (PTY) | Manaus (MAO) | Direct | details |
| Tocumen, Panama City (PTY) | Manta (MEC) | Direct | details |
| Tocumen, Panama City (PTY) | Maracaibo (MAR) | Direct | details |
| Tocumen, Panama City (PTY) | Mendoza (MDZ) | Direct | details |
| Tocumen, Panama City (PTY) | Miami, FL (MIA) | Direct | details |
| Tocumen, Panama City (PTY) | Ministro Pistarini, Buenos Aires (EZE) | Direct | details |
| Tocumen, Panama City (PTY) | Montego Bay (MBJ) | Direct | details |
| Tocumen, Panama City (PTY) | Monterrey (MTY) | Direct | details |
| Tocumen, Panama City (PTY) | Montevideo (MVD) | Direct | details |
| Tocumen, Panama City (PTY) | Nassau (NAS) | Direct | details |
| Tocumen, Panama City (PTY) | O'Hare, Chicago, IL (ORD) | Direct | details |
| Tocumen, Panama City (PTY) | Orlando, FL (MCO) | Direct | details |
| Tocumen, Panama City (PTY) | Palmerola Intl., Tegucigalpa (XPL) | Direct | details |
| Tocumen, Panama City (PTY) | Paramaribo (PBM) | Direct | details |
| Tocumen, Panama City (PTY) | Pereira (PEI) | Direct | details |
| Tocumen, Panama City (PTY) | Philip S.W. Goldson, Belize City (BZE) | Direct | details |
| Tocumen, Panama City (PTY) | Pierre Elliott Trudeau, Montreal (YUL) | Direct | details |
| Tocumen, Panama City (PTY) | Port of Spain (POS) | Direct | details |
| Tocumen, Panama City (PTY) | Porto Alegre (POA) | Direct | details |
| Tocumen, Panama City (PTY) | Punta Cana (PUJ) | Direct | details |
| Tocumen, Panama City (PTY) | Quito (UIO) | Direct | details |
| Tocumen, Panama City (PTY) | Rosario (ROS) | Direct | details |
| Tocumen, Panama City (PTY) | Saint Maarten (SXM) | Direct | details |
| Tocumen, Panama City (PTY) | San Andres Island (ADZ) | Direct | details |
| Tocumen, Panama City (PTY) | San Francisco, CA (SFO) | Direct | details |
| Tocumen, Panama City (PTY) | San Jose (SJO) | Direct | details |
| Tocumen, Panama City (PTY) | San Pedro Sula (SAP) | Direct | details |
| Tocumen, Panama City (PTY) | San Salvador (SAL) | Direct | details |
| Tocumen, Panama City (PTY) | Santa Clara (SNU) | Direct | details |
| Tocumen, Panama City (PTY) | Santa Cruz (VVI) | Direct | details |
| Tocumen, Panama City (PTY) | Santa Marta (SMR) | Direct | details |
| Tocumen, Panama City (PTY) | Santiago (SCL) | Direct | details |
| Tocumen, Panama City (PTY) | Santiago (STI) | Direct | details |
| Tocumen, Panama City (PTY) | Tampa, FL (TPA) | Direct | details |
| Tocumen, Panama City (PTY) | Valencia (VLN) | Direct | details |
|
| From | Destination | Type |
|---|
| Atlanta, GA (ATL) | Tocumen, Panama City (PTY) | Direct | details |
| Austin, TX (AUS) | Tocumen, Panama City (PTY) | Direct | details |
| Baltimore, MD (BWI) | Tocumen, Panama City (PTY) | Direct | details |
| Denver, CO (DEN) | Tocumen, Panama City (PTY) | Direct | details |
| Dulles, Washington, DC (IAD) | Tocumen, Panama City (PTY) | Direct | details |
| Edward L. Logan, Boston, MA (BOS) | Tocumen, Panama City (PTY) | Direct | details |
| Fort Lauderdale, FL (FLL) | Tocumen, Panama City (PTY) | Direct | details |
| HARRY REID INTL AIRPORT, Las Vegas, NV (LAS) | Tocumen, Panama City (PTY) | Direct | details |
| John F. Kennedy, New York, NY (JFK) | Tocumen, Panama City (PTY) | Direct | details |
| Los Angeles, CA (LAX) | Tocumen, Panama City (PTY) | Direct | details |
| Miami, FL (MIA) | Tocumen, Panama City (PTY) | Direct | details |
| O'Hare, Chicago, IL (ORD) | Tocumen, Panama City (PTY) | Direct | details |
| Orlando, FL (MCO) | Tocumen, Panama City (PTY) | Direct | details |
| San Francisco, CA (SFO) | Tocumen, Panama City (PTY) | Direct | details |
| Tampa, FL (TPA) | Tocumen, Panama City (PTY) | Direct | details |